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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">MRP</journal-id><journal-title-group><journal-title>Medical Research and Practice</journal-title></journal-title-group><issn>2993-9690</issn><eissn>2993-9704</eissn><publisher><publisher-name>Art and Design</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/MRP.2025100009</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>ER相关信号通路对乳腺癌的影响研究进展</title><url>https://artdesignp.com/journal/MRP/3/10/10.61369/MRP.2025100009</url><author>陈慧珠,李鑫</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>3</volume><issue>10</issue><history><date date-type="pub"><published-time>2025-10-20</published-time></date></history><abstract>雌激素受体（ER）参与人体多种复杂生理过程，异常的激素信号传导会导致多种疾病的发生，如癌症、炎症和心血管等疾病。其中癌症包括乳腺癌、卵巢癌、宫颈癌和子宫内膜癌等多种妇科肿瘤，临床上以乳腺癌较多见。乳腺癌是激素依赖性肿瘤，体内激素水平通过与ER结合影响其发生发展，因此ER对乳腺癌的治疗起着重要作用。本文将ER与乳腺癌治疗联系并进行总结，为进一步研究ER与乳腺癌治疗之间的机制提供理论基础，为后续乳腺癌治疗及改善患者的预后提供研究思路。</abstract><keywords>雌激素受体,乳腺癌,治疗</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>&amp;nbsp;[1] Liang Y, Zhang H, Song X, Yang Q. 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