MRPMedical Research and Practice2993-96902993-9704Art and Design10.61369/MRP.2025100010Article富血小板血浆联合MEEK植皮技术在大面积烧伤中的临床应用https://artdesignp.com/journal/MRP/3/10/10.61369/MRP.2025100010李昕,巩振中,李金松,牟斌20253102025-10-20目的:探讨富血小板血浆在大面积烧伤病人中联合MEEK植皮技术与单独应用MEEK植皮技术修复创面速度效果对比分析。方法：2024年1月-2025年7月，哈尔滨市第五医院烧伤科收治6例符合盒入选标准的大面积病人，其中男患者5例，女患者1例，年龄在年龄18岁至60岁之间，烧伤总面积50%≤TBSA≤90%，深Ⅱ°~Ⅲ°烧伤，无吸入性损伤、无基础性疾病。致伤原因为热力烧伤，伤后24小时内入院，伤后3-6天有手术适应证。    排除重度基础性疾病及中重度贫血患者，随机将患肢分为Meek植皮+PRP组和单纯Meek植皮组；术后6d、8d、10    d分次换药，观察MEEK微型皮片成活和融合情况，术后10    d，对2组行MEEK微型皮片移植区域统计计算算皮片成活率。术后10    天，在实验区域及对照区域对称部位取成活皮片基底组织，进行微血管计数。术后6天、8天    、10天换药见6天时实验组与对照组创面均较湿润，分泌物相当，10天时实验组创面明显干燥，对照组仍略有湿润，有少量分泌物，去除双绉纱见实验组明显融合成片,皮片融合率（85±4)%（t=3.622,p<0.01)，微血管分部密集,对照组虽已部分融合明显较实验组少，皮片融合率（78±5)%，(t=4.212    p<0.01)微血管分布散在，分泌物略多。结果：富血小板血浆联合MEEK植皮技术较单纯应用MEEK植皮技术在大面积烧伤病人创面修复中愈合速度更快，可缩短病程，提高重病人治愈率。Meek植皮,富血小板血浆,大面积烧伤

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