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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">MRP</journal-id><journal-title-group><journal-title>Medical Research and Practice</journal-title></journal-title-group><issn>2993-9690</issn><eissn>2993-9704</eissn><publisher><publisher-name>Art and Design</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/MRP.2025100020</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>HIV/AIDS合并肝脏疾病危险因素及治疗的研究进展</title><url>https://artdesignp.com/journal/MRP/3/10/10.61369/MRP.2025100020</url><author>卢艳思,周昌静,余小舒</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>3</volume><issue>10</issue><history><date date-type="pub"><published-time>2025-10-20</published-time></date></history><abstract>随着高效抗逆转录病毒治疗（ART）的出现，HIV/AIDS患者的寿命得到显著的延长，而非艾滋病定义性疾病（NADIs）正逐步成为影响HIV/AIDS患者生活质量和引发死亡的主要原因，特别是肝脏疾病；和普通人群相比，HIV感染者的肝脏疾病负担明显更重，而且病因复杂无序、管理难度大，成为当下亟待处理的难题。本文概述了HIV/AIDS &amp;nbsp; &amp;nbsp;合并肝脏疾病的国内外流行病学及总结不同地区的病谱差异，并对目前的治疗现状和面临的挑战进行了探讨，旨在从多个层面为疾病的防治提供理论依据。</abstract><keywords>HIV/AIDS,肝脏疾病,流行病学,危险因素</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>&amp;nbsp;[1] Lemoine M, Serfaty L, Capeau J. 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